Cytotoxic activity screening of some medicinal plants from south of Iran

Authors

  • M. Hamzeloo-Moghadam Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences,Tehran, Iran. Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • M. Mosaddegh Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences,Tehran, Iran. Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • S. Esmaeili Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences,Tehran, Iran. Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • S. Ghaffari Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences,Tehran, Iran.
Abstract:

Background and objectives: Cancer is a public health problem all over the world. Herbal medicines have a vital role in the prevention and treatment of cancer and large numbers of plants and their isolated constituents have shown potential anticancer activity. Methods: Twenty seven medicinal plants from southern Iran provinces have been extracted with methanol and screened for their cytotoxic activity against MCF-7, WEHI-164, HepG-2, MDBK and A-549 cell lines by MTT assay. Results: The methanol extracts of two species, Calotropis procera andJuniperus excelsa, demonstrated to be more effective compared to other extracts. Conclusion: The above species are proper candidates for further cancer studies.  

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Journal title

volume 1  issue 4

pages  19- 25

publication date 2014-10-01

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